Cavani last month shared an Instagram story from a fan which featured a racially offensive term after United's 3-2 win at Southampton, in which Cavani scored twice, including a stoppage-time winner.
The post was later deleted, and Cavani apologised for any unintentional offence caused.
Meanwhile, Manchester United said that the post was clearly used in an affectionate manner and has different connotations in Cavani's home country of Uruguay.
But the FA have seen fit to charge the striker with a breach of their Rule E3, alleging his post was "insulting and/or abusive and/or improper and/or brought the game into disrepute.
"It is further alleged that the comment constitutes an Aggravated Breach, which is defined in FA Rule E3.2, as it included reference, whether express or implied, to colour and/or race and/or ethnic origin," the governing body said.
Cavani has until January 4 to respond to the charge.




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